Status:

RECRUITING

Validation of the Prognostic Impact of a Retinal Photograph-based Cardiovascular Disease Risk Stratification System in de Novo HFrEF

Lead Sponsor:

Yonsei University

Conditions:

Heart Failure

Cardiomyopathies

Eligibility:

All Genders

20+ years

Brief Summary

"Despite significant advances in pharmacologic and device-based therapies, heart failure (HF) remains a major public health burden, with persistently high rates of hospitalization, impaired quality of...

Detailed Description

"Study Methods 1. Eligible participants will be approached during outpatient visits or hospitalization. The purpose and procedures of the study will be explained in detail, and informed consent will ...

Eligibility Criteria

Inclusion

  • Patients aged between 20 and 79 years with a left ventricular ejection fraction of 40% or less (assessed by transthoracic echocardiography), who have provided written consent for participation, have the capability to consent voluntarily

Exclusion

  • Inability to obtain high-quality fundus photographs due to severe ophthalmologic conditions
  • Presence of extensive retinal diseases that significantly impair visualization of the retinal vasculature
  • Decline to provide informed consent for study participation, including:
  • Pregnant individuals
  • Individuals lacking decision-making capacity

Key Trial Info

Start Date :

December 10 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 10 2030

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06978998

Start Date

December 10 2024

End Date

December 10 2030

Last Update

May 18 2025

Active Locations (1)

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1

Severance hospital

Seoul, South Korea