Status:
RECRUITING
Enhanced White Light Endoscopy Versus Conventional White Light Endoscopy for Colorectal Adenoma Detection: A Randomized Controlled Trial
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Colorectal Adenoma
Eligibility:
All Genders
45-85 years
Phase:
NA
Brief Summary
1. Study on Adenoma Detection Rate (ADR) Comparing Enhanced White Light Endoscopy (E-WLI) versus Conventional White Light Endoscopy (WLI); 2. Study Comparing Enhanced White Light Endoscopy (E-WLI) ver...
Detailed Description
Before colonoscopy, gastroenterology specialists stratified eligible patients according to 1) colorectal cancer screening, 2) positive fecal immunochemical test (FIT) results or gastrointestinal sympt...
Eligibility Criteria
Inclusion
- 1\. Male or female aged 45 to 85
- 2\. Patients undergoing colonoscopy for colorectal cancer screening, positive fecal immunochemical test (FIT) results, gastrointestinal symptoms, or follow-up examination after colorectal polyp treatment
- 3\. Capable of providing informed consent and agreeing to participate
- 4\. Able and willing to follow all research processes
Exclusion
- 1\. Participated in other clinical trials, signed informed consent form, and in the follow-up period of other clinical trials;
- 2\. Participated in clinical trials of drugs and is in the discontinuation period of experimental or control drugs;
- 3\. Have had drug or alcohol abuse or psychological disorders in the past five years.
- 4\. Pregnant or lactating patients;
- 5\. Known to have polyposis syndrome;
- 6\. Patients with gastrointestinal bleeding;
- 7\. Previous history of inflammatory bowel disease, colorectal cancer, or colorectal surgery;
- Patients with contraindications to tissue biopsy;
- 9\. History of allergies to the ingredients in intestinal cleansers;
- 10\. Individuals with conditions such as intestinal obstruction or perforation, toxic megacolon, heart failure (grade III or IV), severe cardiovascular disease, severe liver failure, or renal insufficiency, among others.
- 11\. Researchers believe that patients are not suitable to participate in the trial.
Key Trial Info
Start Date :
September 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2026
Estimated Enrollment :
800 Patients enrolled
Trial Details
Trial ID
NCT06979232
Start Date
September 20 2025
End Date
May 31 2026
Last Update
October 2 2025
Active Locations (7)
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1
Chongqing General Hospital
Chongqing, Chongqing Municipality, China
2
The First People's Hospital of Lanzhou City
Lanzhou, Gansu, China, 730050
3
The Third Affiliated Hospital of Heilongjiang University of Chinese Medicine
Harbin, Heilongjiang, China, 150030
4
Armed Police Forces Hospital of Sichuan
Leshan, Sichuan, China