Status:

RECRUITING

Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI

Lead Sponsor:

The University of Hong Kong

Conditions:

Gum Disease

Prediabetes

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Prediabetes is an intermediate stage before the development of diabetes, characterized by elevated blood glucose levels but lower than the diagnostic criteria of diabetes and is associated with multip...

Detailed Description

Prediabetes is an intermediate stage before the development of diabetes, characterized by elevated blood glucose levels but lower than the diagnostic criteria of diabetes and is associated with multip...

Eligibility Criteria

Inclusion

  • \- Subjects who are \>18 years of age and able to give informed consent.
  • \- Subjects who are mentally and cognitively healthy.
  • \- Subjects who have at least 6 anterior maxillary or mandibular natural teeth including incisors and canine.
  • \- Subjects who are with prediabetic state with impaired HbA1c 5.7% to 6.4%, impaired fasting plasma glucose level 5.6mmol/L to 6.9 mmol/L and/or impaired plasma glucose level after 2h OGTT 7.8 mmol/L to 11.0 mmol/L.
  • \- Subjects who can speak, read, or understand Cantonese to complete the satisfaction questionnaire.
  • \- Subjects who can practice oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) daily on their own independently.

Exclusion

  • \- Subjects who have less than 6 anterior maxillary or mandibular natural teeth with or without dental prostheses in those area.
  • \- Subjects who are with a current diagnosis or clinical history of T2DM.
  • \- Subjects who have mental illness, or similar problems that unable to complete the satisfaction questionnaire.
  • \- Subjects who cannot perform oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) by any condition of oral cavity such as tumor or maxillomandibular fixation.

Key Trial Info

Start Date :

April 12 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 18 2026

Estimated Enrollment :

148 Patients enrolled

Trial Details

Trial ID

NCT06980701

Start Date

April 12 2025

End Date

April 18 2026

Last Update

December 3 2025

Active Locations (1)

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1

Prince Philip Dental Hospital

Hong Kong, Sai Ying Pun, Hong Kong, 999077