Status:
RECRUITING
ZeroHeart Biopsy - Prediction of Deceased Donor Heart Transplant Performance From Organ Donors Using Pre-Transplant Biopsies - A Pilot Study
Lead Sponsor:
Medical University of Vienna
Collaborating Sponsors:
Alberta Transplant Applied Genomics Centre
Conditions:
Heart Transplantation
Graft Rejection
Eligibility:
All Genders
Brief Summary
The goal of this observational study is to evaluate whether molecular analysis of donor heart biopsies taken at the time of organ removal ("Time Zero") can help predict the future function and rejecti...
Eligibility Criteria
Inclusion
- All hearts from standard and expanded criteria donors as well as donor hearts from Donation after circulatory death (DCD) undergoing a heart biopsy at pre-implantation (at procurement) will be included. Consent will be obtained from the recipient at the time of transplant listing.
Exclusion
- Hearts will be excluded from the study if the participating clinician decides to discard the organ before transplantation or the recipient declines that the biopsy will be performed at the organ procurement.
Key Trial Info
Start Date :
May 12 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2028
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06982404
Start Date
May 12 2025
End Date
May 31 2028
Last Update
May 21 2025
Active Locations (1)
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1
Medical University Vienna
Vienna, Vienna, Austria, 1090