Status:

NOT_YET_RECRUITING

Persistence of Oral DNA Adducts in Smokers and Vapers

Lead Sponsor:

University of Minnesota

Conditions:

Smokers

Vaping

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

This study aims to better understand what damage caused to oral cells from smoking and vaping might be important in the formation of oral cancers. We will compare levels of DNA damage between those as...

Detailed Description

DNA damage (adducts) in the oral cells will be measured in people who smoke and vape while they are using their products regularly for two weeks. Then half of the participants will be asked to stop sm...

Eligibility Criteria

Inclusion

  • 21+ years old
  • Good physical and mental health
  • Stable physical and mental health
  • Either 1) smokes cigarettes daily, 2) vapes daily, 3) does not use any tobacco or nicotine products

Exclusion

  • Pregnant or nursing
  • High blood pressure
  • Unstable health condition(s)
  • History of cancer or liver disease

Key Trial Info

Start Date :

January 31 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 30 2030

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT06983392

Start Date

January 31 2026

End Date

July 30 2030

Last Update

August 26 2025

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