Status:
RECRUITING
Reducing Symptom Burden Through Physical Exercise in Melanoma Patients
Lead Sponsor:
Universität Duisburg-Essen
Conditions:
Malignant Melanoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of the clinical trial is to determine whether regular exercise can reduce fatigue in adult patients with stage IIb-IV melanoma undergoing immunotherapy or targeted therapy. Additionally, we wi...
Eligibility Criteria
Inclusion
- patients ≥ 18 years with malignant melanoma (Stage IIb - IV) receiving adjuvant immuno- or targeted therapy
- patients already on the same treatment protocol for at least 3 months
- sufficient knowledge of German
- completed and signed written consent form and completed medical history form
- medical clearance for the exercise program and performance diagnostics
- ability to participate in the exercise program
- willingness to visit the study hospital for training sessions and examinations
Exclusion
- confirmation of contraindications for physical exercise by the attending physician (e.g. fracture risk in the case of bone metastases)
- untreated, symptomatic, known brain metastases
- severe neurological or cardiac impairment according to ACSM criteria
- confirmation of respiratory insufficiency by the attending physician
- life expectancy less than 3 months
- physical or mental conditions that would not allow implementation of the exercise program or study protocol
- excessive physical activity (i.e. \>150 minutes/week of moderate to intense physical activity and systematic intense strength/endurance training at least twice a week for one hour)
Key Trial Info
Start Date :
August 18 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2027
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT06985056
Start Date
August 18 2025
End Date
November 1 2027
Last Update
August 19 2025
Active Locations (1)
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1
University Hospital Essen
Essen, Germany, 45147