Status:
ACTIVE_NOT_RECRUITING
Complementary Behavioral Interventions To Remediate Cognitive Impairment or Emotional Distress in Cancer Survivors
Lead Sponsor:
St. Jude Children's Research Hospital
Conditions:
Survivors of Childhood Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Childhood cancer survivors are at risk for accelerated aging due to the specific treatments they have received to cure their cancer. Several interventions, including exercise, cognitive training, and ...
Detailed Description
The study will recruit survivors from the SJLIFE cohort who have completed a recent SJLIFE campus visit and were pre-identified as either cognitively (by self-report on Childhood Cancer Survivor Study...
Eligibility Criteria
Inclusion
- Participants enrolled in St. Jude Lifetime Cohort (SJLIFE) \>18 years of age.
- Participant has been pre-identified as both physically impaired (T score ≤45 on the physical function and/or role physical subscales of the Medical Outcomes Survey Short Form 36 (SF-36)), and either cognitively (standard score \>84th percentile on the Childhood Cancer Survivor Study Neurocognitive Questionnaire) or emotionally impaired (T scored score ≥ 63 on the Brief Symptom Inventory) from the most recently completed SJLIFE survey questionnaires.
- Participant self-reports participating in \<150 minutes of moderate to vigorous physical activity per week (Centers for Disease Control Physical Activity Guidelines for Americans).
- Participant has been medically cleared to participate in physical activity.
- Participant verbalizing understanding of the directions to use the digital platform on provided laptop/tablet.
Exclusion
- Participant cannot speak, read, and/or understand English.
- Participant is a woman and currently pregnant.
- Participant reports engaging in mindfulness-based training or continuously practiced mindfulness techniques over the past 6 weeks.
- Participant has an estimated intelligence score (FSIQ) \<80.
- Participant has a diagnosis of post-traumatic stress disorder, major psychiatric condition, and/or history of suicidal ideation or self-harm.
- Participant reports alcohol or drug abuse in the past year (Alcohol Use Disorders Identification Test (AUDIT) \>=13/women and \>=15/men or Drug Abuse Screen Test (DAST) -10\>3).
Key Trial Info
Start Date :
July 29 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06989463
Start Date
July 29 2025
End Date
November 1 2026
Last Update
December 18 2025
Active Locations (1)
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1
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105