Status:

RECRUITING

Transcranial Direct Current Stimulation and Modulation of Affect and Pain

Lead Sponsor:

Trustees of Dartmouth College

Conditions:

We Are Not Studying a Disease or Condition

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

This double-blind randomized crossover study aims to examine the effects of left primary motor cortex (M1) tDCS on evoked thermal pain perception, pain-related decision making, and placebo effects by ...

Detailed Description

This study aims to examine the effects of M1 tDCS on induced experimental pain, pain-related decision making, and independently manipulate expectations based on the pain and monetary offered by others...

Eligibility Criteria

Inclusion

  • ages 18-55
  • Participants must be capable of performing experimental tasks (e.g., are able to read)
  • Fluent or native speakers of English

Exclusion

  • No self-reported current or history of depression, bipolar disorder, or other psychiatric diagnosis.
  • No self-reported current seizure disorder (i.e., seizure within past 10 years)
  • No history of stroke or other major neurological diagnosis.
  • No self-reported current chronic pain, or acute pain within three months of the study period.
  • No current migraine disorder (i.e., 15 headache days or more in 1 month).
  • No use of central nervous system-effective medication or other medication for neurological/psychiatric treatment. No self-reported substance abuse within the last six months.
  • No contraindication to MRI or tDCS (e.g., pregnancy, claustrophobia, pacemakers, ear/cochlear implants, shrapnel injuries, clips, or other ferromagnetic/electrical objects/devices, diagnosed brain abnormality such as tumor, or skin lesions on the scalp.).
  • No contraindications for induced pain (e.g., no heart disease, high blood pressure, heart surgery, heart problems of any kind, severe asthma, respiratory problems of any kind, fibromyalgia, Raynaud's Syndrome or Disease, chronic pain, diabetes).

Key Trial Info

Start Date :

September 9 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06989749

Start Date

September 9 2023

End Date

September 1 2026

Last Update

May 25 2025

Active Locations (1)

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1

Dartmouth College

Hanover, New Hampshire, United States, 03755

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