Status:
ENROLLING_BY_INVITATION
Deflated and Inflated Cuff Endotracheal Extubations
Lead Sponsor:
Naval Medical Center Camp Lejeune
Conditions:
Anesthesia Airway Management
Respiratory Complications
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
General anesthesia is a treatment with medicine to make a patient unconscious for surgery. This is sometimes called "being put to sleep" or "being put under." Most of the time, a breathing tube is use...
Detailed Description
The current standard anesthetic practice for extubation is to deflate the endotracheal tube cuff using a syringe prior to extubation. While commonplace and nearly universally accepted, this practice i...
Eligibility Criteria
Inclusion
- Adults aged 18 to 50 years old
- Scheduled for surgery, not of the airway, head, or neck, with anticipated case duration of less than 3 hours
- American Society of Anesthesiologists (ASA) Physical Status Classification of 1 to 3
Exclusion
- Emergent surgery, or surgery requiring prone, sitting or lateral positioning
- Pre-existing laryngeal pathology, obstructive pulmonary disease, pulmonary hypertension, interstitial lung disease, active respiratory infection, recent pneumonia, uncontrolled asthma, or uncontrolled gastroesophageal reflux disease
- Known difficulties with general anesthesia, such as prior anaphylactic reaction, difficult intubation or mask ventilation
- Known allergy to iohexol or a previous severe reaction to any contrast agents
- Unfavorable airway examination, such as Mallampati 4, limited mouth opening, and/or inability to extend neck
- Non-compliance with ASA Practice Guidelines for Preoperative Fasting
- Pregnancy
- Enrollment in another anesthesiology or surgery related interventional research study
- Surgeries scheduled on Friday or a day immediately prior to a holiday
Key Trial Info
Start Date :
June 17 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT06990308
Start Date
June 17 2025
End Date
September 1 2026
Last Update
December 16 2025
Active Locations (1)
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1
Naval Medical Center Camp Lejeune
Marine Corps Base Camp Lejeune, North Carolina, United States, 28547