Status:

NOT_YET_RECRUITING

Impact of Probiotics on Antibiotic-associated Diarrhea in Community-acquired Pneumonia

Lead Sponsor:

National Health Insurance Service Ilsan Hospital

Conditions:

Pneumonia

Probiotics

Eligibility:

All Genders

19-79 years

Phase:

PHASE4

Brief Summary

The study goal is to determine whether oral administration of a probiotic mixture can reduce the incidence of antibiotic-associated diarrhea in patients with community-acquired pneumonia.

Eligibility Criteria

Inclusion

  • Adult patients aged 19 years or older admitted with a diagnosis of community-acquired pneumonia
  • Patients eligible for oral medication administration (able to take oral or enteral feeding)

Exclusion

  • Sepsis patients
  • Patients admitted to the intensive care unit (ICU) following endotracheal intubation
  • Elderly patients aged 80 years or older
  • Pregnant women
  • Patients who have diarrhea at the time of admission
  • Patients with a history of using probiotics within 3 months prior to admission
  • Patients with a history of using laxatives within 1 week prior to admission
  • Patients suspected of being in shock (mean arterial pressure \< 65 mmHg) at the time of admission

Key Trial Info

Start Date :

June 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06990568

Start Date

June 1 2025

End Date

December 31 2026

Last Update

May 25 2025

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