Status:

NOT_YET_RECRUITING

Investigating the Effectiveness of a 2-week Novel Non-invasive Brain Stimulation Technique on Cognitive Outcomes in Healthy Adults

Lead Sponsor:

Nanyang Technological University

Collaborating Sponsors:

Ministry of Education, Singapore

National Institute of Education, Singapore

Conditions:

Transcranial Direct Current Stimulation (tDCS)

Ageing

Eligibility:

All Genders

21-75 years

Phase:

NA

Brief Summary

The goal of this randomised controlled trial is to investigate the effects of a 2-week high-frequency transcranial pulsed current stimulation (tPCS) on cognitive outcomes in older and healthy adults. ...

Detailed Description

tPCS / tDCS and sham-tPCS will be administered between 0.6 to 0.7 mA for 20 minutes. This will take place over 10 consecutive sessions, with a 2 day break between days 5 and 6 of brain stimulation. Th...

Eligibility Criteria

Inclusion

  • Male and female young (21 to 30 years) and older adults (60 to 75 years)
  • Right-handed
  • Must be a native English speaker
  • No clinical diagnosis of neurodevelopmental, mood, neurological or neurodegenerative disorders
  • Adults with cardiometabolic or cardiovascular conditions may participate if their condition is controlled and stable with medication and / or lifestyle interventions

Exclusion

  • Currently on long-term medication for pain or migraines / headaches
  • Adults with metallic implants in the chest or head region
  • Adults with epilepsy, or known seizure or immediate family members that have had a seizure before
  • Had a recent head injury that resulted in a temporary loss of consciousness or of memory in the last 12 months
  • Had prior head surgery
  • Prone to fainting
  • Sensitive skin or prone to skin allergies

Key Trial Info

Start Date :

June 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2027

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06991764

Start Date

June 1 2025

End Date

April 30 2027

Last Update

May 28 2025

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