Status:

COMPLETED

Clinical Evaluation of Long-term Sequelae in Patients With Severe Plasmodium Falciparum Malaria

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Falciparum Malaria

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Malaria, endemic in 85 countries, remains a major concern. By 2022, there will be 249 million cases and 608,000 deaths, 94% of them in Africa. In France, 4995 cases of imported malaria were reported i...

Eligibility Criteria

Inclusion

  • Male or female over 18 years of age
  • Have been diagnosed with severe malaria according to WHO criteria and have been treated between 1/1/2018 and 321/12/2024 at the AP-HM
  • Have been treated with Artesunate IV (MALACEF®) (at least one dose)
  • Patient who has received information about the study and has not expressed opposition
  • Patient benefiting or entitled to benefit from a social security scheme

Exclusion

  • Patients with advanced neurodegenerative pathology pre-existing the malaria attack
  • Subjects covered by articles L1121-5 to 1121-8 of the Public Health Code (minor patients, patients of legal age under guardianship, curatorship or safeguard of justice, patients deprived of their liberty, pregnant or breast-feeding women),
  • Persons who do not understand French

Key Trial Info

Start Date :

June 17 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 13 2025

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT06992297

Start Date

June 17 2025

End Date

September 13 2025

Last Update

December 5 2025

Active Locations (1)

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Assistance Publique Hopitaux de Marseille

Marseille, France, 13354