Status:

NOT_YET_RECRUITING

The Predictability of CD19 Expression Across Primitive Cellular Fractions of Relapsed B-ALL on Outcomes of CD19-targeted CAR T-cells

Lead Sponsor:

King Faisal Specialist Hospital & Research Center

Conditions:

Relapsed B-ALL

CAR T-cells

Eligibility:

All Genders

Brief Summary

Acute lymphoblastic leukemia (ALL) is a malignant proliferation of immature lymphoid cells within the bone marrow, blood, and extramedullary sites. According to the SEER Cancer Statistics Review, the ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • All patients (adults and pediatrics) with confirmed diagnosis with B-ALL and receipt CD19-targeted CAR-T cell therapy and have diagnostic or post -treatment BM or PB samples processed with a standard B-ALL immunophenotyping panel. with the presence of CD45, CD19, CD34, and CD38 in the antibody panel.

Exclusion

    Key Trial Info

    Start Date :

    May 20 2025

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    May 31 2030

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT06993766

    Start Date

    May 20 2025

    End Date

    May 31 2030

    Last Update

    May 29 2025

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