Status:

RECRUITING

Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients

Lead Sponsor:

Uşak University

Conditions:

Diabetic Group (n=30)

Non-diabetic Group

Eligibility:

All Genders

50-80 years

Phase:

NA

Brief Summary

By comparing DEL-1 and IL-17 levels in the aqueous humor of diabetic cataract patients with the aqueous humor of non-diabetic patients, we aim to understand the biochemical effects of diabetes-related...

Detailed Description

Developmental Endothelial Locus-1 (DEL-1) is a molecule related to endothelial cells and is a protein involved in intercellular interactions. It is generally associated with the development and functi...

Eligibility Criteria

Inclusion

  • Cataract diagnosed and surgery planned
  • Patients without any other ocular pathology other than cataract.
  • Type 2 DM for at least 5 years in the diabetic group

Exclusion

  • Patients with previous intraocular surgery
  • Those with inflammatory eye diseases (e.g. uveitis)
  • Those with autoimmune diseases or systemic inflammatory diseases
  • Those receiving local or systemic steroid therapy
  • Those with severe systemic disease (e.g. advanced renal failure, malignancy)

Key Trial Info

Start Date :

May 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 15 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06995131

Start Date

May 1 2025

End Date

August 15 2025

Last Update

June 5 2025

Active Locations (1)

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Uşak Training and Research Hospital

Uşak, Uşak, Turkey (Türkiye), 64000