Status:
RECRUITING
Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery
Lead Sponsor:
Ain Shams University
Conditions:
Post-spinal Hypotension
Orthopedic Surgery
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elec...
Detailed Description
Spinal anesthesia is commonly used for orthopedic procedures due to its effectiveness and favorable recovery profile. However, spinal-induced hypotension is a frequent complication resulting from symp...
Eligibility Criteria
Inclusion
- Patients American Society of Anesthesiologists Physical Status (ASA) I to II undergoing orthopedic surgeries under spinal anesthesia.
- Both Sexes.
- Patients aged equal to or above 18 years.
- Body mass index \<35 kg/m2
- Duration of operation from 1 hour to 3 hours
Exclusion
- Patients' refusal of procedure or participation in the study.
- Patients with contraindication to spinal anesthesia.
- Patients with cardiovascular or pulmonary disease.
- Patients with pre-procedural hypotension (systolic arterial pressure less than 90 mmHg and/or mean arterial pressure less than 60 mmHg).
- Patients aged below 18 years.
- Duration of operation below 1 hour or above 3 hours.
Key Trial Info
Start Date :
June 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06995690
Start Date
June 1 2025
End Date
November 1 2025
Last Update
June 18 2025
Active Locations (1)
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1
Ain Shams University Hospitals
Cairo, Egypt