Status:

RECRUITING

Impact of Oral Versus Intravenous 5-FU-Based Adjuvant Regimens on Sleep Quality and Depression in Patients With Gastrointestinal Cancers

Lead Sponsor:

Ankara Etlik City Hospital

Conditions:

Gastrointestinal Neoplasms

Eligibility:

All Genders

18+ years

Brief Summary

This prospective, non-randomized, single-center observational study is designed to investigate the effects of oral versus intravenous (IV) 5-fluorouracil (5-FU)-based adjuvant chemotherapy regimens on...

Detailed Description

This is a prospective, non-randomized, single-center observational study designed to investigate the effects of oral versus intravenous (IV) 5-fluorouracil (5-FU)-based adjuvant chemotherapy regimens ...

Eligibility Criteria

Inclusion

  • Histopathologically confirmed non-metastatic gastrointestinal system cancer (e.g., colorectal, gastric)
  • Age ≥18 years
  • Planned to receive adjuvant chemotherapy containing 5-FU (either oral or IV)
  • ECOG performance status 0-2
  • Provided informed consent

Exclusion

  • Patients with psychiatric disorders affecting sleep or mood
  • Receiving treatment for primary sleep disorders or depression
  • Prior chemotherapy or radiotherapy for the current diagnosis
  • Inability to complete the questionnaires due to cognitive or language barriers

Key Trial Info

Start Date :

June 5 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 30 2026

Estimated Enrollment :

82 Patients enrolled

Trial Details

Trial ID

NCT06996483

Start Date

June 5 2025

End Date

January 30 2026

Last Update

January 5 2026

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Ankara Etlik City Hospital

Ankara, Yenimahalle, Turkey (Türkiye), 06210

2

Etlik City Hospital, Medical Oncology Department

Ankara, Yenimahalle, Turkey (Türkiye), 06210

3

Etlik City Hospital

Ankara, Yenimahalle, Turkey (Türkiye), 06210