Status:

RECRUITING

Study to Compare the Clinical Effectiveness and Cost Utility of an All-in-one Procedure With an At-home Screening Trial

Lead Sponsor:

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Conditions:

Neuromodulation

Chronic Pain Patients

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In 2019, the Dutch Healthcare Institute published a consensus report outlining when spinal cord stimulation (SCS) for chronic pain qualifies for reimbursement under Dutch health insurance. It mandates...

Eligibility Criteria

Inclusion

  • Diagnosed with chronic, neuropathic pain with an approved aetiology in the Netherlands PSPS (persistent spinal pain syndrome) PDN (painful diabetic neuropathy) CRPS (complex regional pain syndrome) SFN (small fibre neuropathy)
  • Suitable candidate according to the inclusion criteria of the Dutch "Standpoint on Neuromodulation in Chronic Pain" Adult patients ≥18 years Chronic pain ≥6 months Pain intensity of ≥50mm or ≥5 on VAS- or NRS-score respectively
  • Routinely selected for CL-SCS
  • Be willing to complete additional trial related questionnaires
  • Be willing and capable of giving informed consent.

Exclusion

  • General exclusion criteria according to the Dutch "Standpoint on Neuromodulation in Chronic Pain":
  • Drug abuse Pregnancy Coagulation disorder / Use of anticoagulation therapy which cannot be stopped temporarily Active infection Life expectation ≤12 months Intake questionnaires "PROMS neuromodulatie" not completed by the patient
  • Have an existing drug pump and/or SCS system or another active implantable device such as a pacemaker, deep brain stimulator (DBS), or sacral nerve stimulator (SNS)
  • Current or previous treatment with an implanted pain reduction device
  • Participation in another clinical trial that may confound the results of this trial

Key Trial Info

Start Date :

June 6 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2028

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT06996574

Start Date

June 6 2025

End Date

April 1 2028

Last Update

July 10 2025

Active Locations (1)

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1

Amsterdam UMC

Amsterdam, Netherlands