Status:
RECRUITING
Impact of the Novel UC-TREAT Diet on the Gut Microbiome and Its Acceptability in Healthy Adults and Adults With Quiescent Ulcerative Colitis
Lead Sponsor:
University of Glasgow
Conditions:
Ulcerative Colitis (UC)
Eligibility:
All Genders
16+ years
Phase:
NA
Brief Summary
This will be an open-label dietary intervention study recruiting both healthy adults (≥16y) and adults with quiescent Ulcerative Colitis (UC). The study will span a total of 25 days and is divided int...
Detailed Description
This will be an open-label dietary intervention study recruiting both healthy adults (≥16y) and adults with quiescent Ulcerative Colitis (UC) . The study will span a total of 25 days and is divided in...
Eligibility Criteria
Inclusion
- Individuals with Ulcerative Colitis:
- Confirmed diagnosis of Ulcerative Colitis
- ≥16 years of age
- Motivated to follow the prescribed diet for the study period
- Healthy controls:
- ≥16 years of age
- Motivated to follow the prescribed diet for the study period
Exclusion
- Individuals with Ulcerative Colitis:
- Self-reported active disease (SCCAI≥5) and/or a score ≥2 on any variable within SCCAI
- Previous surgery related to their UC (e.g. colectomy)
- Adjustment of medication dose in the previous month
- Initiation of a new medication in the prior 3 months
- BMI≥35kg/m2
- Pregnancy or lactation
- Regular use of pre/probiotic supplements
- Antibiotics or steroid use in the past 2 months
- Weight fluctuations ≥ 2kg in the past month
- Dietary restrictions (vegetarian, vegan, gluten-free etc)
- Participation in other interventional research.
- Healthy controls:
- Regular use of medication or regular visits to a physician
- History of gut surgery
- BMI≥35kg/m2
- Pregnancy or lactation
- Regular use of pre/probiotic supplements
- Antibiotics or steroid use in the past 2 months
- Weight fluctuations ≥ 2kg in the past month
- Dietary restrictions (vegetarian, vegan, gluten-free etc)
- Participation in other interventional research.
Key Trial Info
Start Date :
May 8 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2026
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT06998277
Start Date
May 8 2024
End Date
December 30 2026
Last Update
June 4 2025
Active Locations (1)
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1
University of Glasgow
Glasgow, United Kingdom, G31 2ER