Status:

RECRUITING

Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass

Lead Sponsor:

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Conditions:

Postoperative Cognitive Dysfunction

Delirium, Postoperative

Eligibility:

All Genders

18-70 years

Brief Summary

Neurological dysfunction either transient or permanent is a major cause of morbidity and mortality after cardiopulmonary bypass, and cognitive dysfunction is more frequent in cardiac surgery than in n...

Detailed Description

Patient Selection: Our study is a single-center, prospective, observational study. The study will include 65 patients scheduled for elective coronary artery bypass grafting (CABG) surgery between 01....

Eligibility Criteria

Inclusion

  • Patients aged 18-70
  • Patients scheduled for isolated elective cardiopulmonary bypass surgery

Exclusion

  • Patients with carotid stenosis ≥50%
  • Emergency patients or those with a history of reoperation
  • Patients with a history of cerebrovascular events
  • Patients who do not provide consent
  • Patients with temporal window failure
  • Patients with an ejection fraction (EF) \<40%
  • Patients with a Mini-Mental State Examination (MMSE) score \<23
  • Patients who require mechanical ventilation for more than 24 hours or those who are reintubated

Key Trial Info

Start Date :

April 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 30 2026

Estimated Enrollment :

106 Patients enrolled

Trial Details

Trial ID

NCT07000461

Start Date

April 1 2025

End Date

April 30 2026

Last Update

June 3 2025

Active Locations (1)

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Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Istanbul, Turkey (Türkiye)