Status:
RECRUITING
Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients
Lead Sponsor:
Centre Hospitalier Universitaire de la Guadeloupe
Conditions:
Sickle Cell
Sickle Cell Disease
Eligibility:
All Genders
18+ years
Brief Summary
Sickle cell disease is a chronic disease characterized by multiple vaso-occlusive complications. The basic treatment for patients with a vaso-occlusive crisis (VOC) is based on adequate hydration, oxy...
Detailed Description
Regional anesthesia (RA) possesses intrinsic anti-inflammatory properties and can modulate the inflammatory response. For instance, ropivacaine reduces inflammation induced in vitro in rat epithelial ...
Eligibility Criteria
Inclusion
- patients adult \>18 years
- patients with vaso-occlusive crisis
Exclusion
- Pregnant or breastfeeding women
- Blood transfusion within the last 3 months
- Lack of affiliation with the French social security system
- Protected individuals
Key Trial Info
Start Date :
February 5 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 5 2027
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT07001189
Start Date
February 5 2025
End Date
February 5 2027
Last Update
June 3 2025
Active Locations (1)
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1
Chu de La Guadeloupe
Pointe-à-Pitre, Guadeloupe, 97159