Status:

COMPLETED

Long-term Effects of SCL-wearing on Corneal Neuromediators and Postoperative Rehabilitation After SMILE

Lead Sponsor:

yuhao shao

Collaborating Sponsors:

Shanghai 10th People's Hospital

Conditions:

Contact Lens Complication

Small Incision Lenticule Extraction

Eligibility:

All Genders

18-45 years

Brief Summary

To investigate the effects of neuromediators in corneal stromal lenticules from patients with long-term soft contact lens (SCL) wear on corneal nerve regeneration and visual quality recovery following...

Detailed Description

he prospective cohort study recruited 90 patients who underwent SMILE between June 2023 and June 2024. 90 eyes were categorized into three groups according to the duration of wearing SCL: the \> 10 ye...

Eligibility Criteria

Inclusion

  • age ≥ 18 years with stable refraction for at least two years;
  • corrected distance visual acuity of 20/20 or better;
  • no history of using rigid gas permeable lenses or orthokeratology (OK) lenses prior to examination

Exclusion

  • \- a history of moderate to severe dry eye as well as any ocular or systemic disease that would contraindicate laser refractive surgery.

Key Trial Info

Start Date :

June 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 20 2025

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT07001306

Start Date

June 1 2023

End Date

May 20 2025

Last Update

July 20 2025

Active Locations (1)

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Shanghai Tenth People's Hospital

Shanghai, China