Status:

RECRUITING

Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda

Lead Sponsor:

Washington University School of Medicine

Collaborating Sponsors:

Makerere University

Columbia University

Conditions:

HIV Prevention

Eligibility:

FEMALE

15-24 years

Phase:

NA

Brief Summary

The study will employ a multilevel combination intervention focused on PrEP initiation and adherence among adolescent girls and young women (AGYW) (aged 15-24) living in HIV hotpots in Uganda. Specifi...

Detailed Description

Adolescent girls and young women (AGYW) aged 15-24 are twice as likely to be living with HIV than young men in Sub-Saharan Africa (SSA). HIV prevention strategies available to AGYW primarily depend on...

Eligibility Criteria

Inclusion

  • Age 15-24 years
  • At a high risk of HIV. AGYW will be deemed to be at substantial risk, and eligible to participate in the study, if they report at least one of the seven high-risk sexual behaviors on the risk assessment tool: 1) vaginal/anal sexual intercourse with more than one partner of unknown HIV status in the past six months, 2) vaginal/anal sex without a condom in the past six months, 3) sex in exchange for money, goods or a service in the last six months, 4) injecting drugs in the past six months, 5) diagnosis with an STI more than once in the past twelve months, 6) post-exposure prophylaxis (PEP) for sexual exposure to HIV in the past six months, and 7) having an HIV-infected sexual partner who was not on ART.

Exclusion

  • HIV positive
  • Unable to understand the study procedures and/or participant rights during the informed consent process
  • Unwilling or unable to commit to completing the study

Key Trial Info

Start Date :

October 20 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2029

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT07002866

Start Date

October 20 2025

End Date

December 31 2029

Last Update

November 5 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Washington University in St. Louis

St Louis, Missouri, United States, 63130

2

International Center for Child Health and Development (ICHAD)

Masaka, Uganda