Status:

RECRUITING

Sarcopenia and Neuromuscular Block in Gastrointestinal Cancer Surgery

Lead Sponsor:

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Conditions:

Gastrointestinal Cancer

Sarcopenia

Eligibility:

All Genders

18-75 years

Brief Summary

This prospective observational study aims to evaluate the effects of sarcopenia on intraoperative neuromuscular block (NMB) in patients undergoing gastrointestinal cancer surgery. Adult patients sched...

Detailed Description

Sarcopenia, characterized by the loss of skeletal muscle mass and function, is a significant clinical parameter affecting both prognosis and perioperative management in patients with gastrointestinal ...

Eligibility Criteria

Inclusion

  • Patients aged between 18 and 75 years
  • Patients diagnosed with gastrointestinal system (GIS) cancer and scheduled for elective surgery
  • Patients who have undergone preoperative abdominal computed tomography (CT) imaging
  • Patients classified as American Society of Anesthesiologists (ASA) physical status I-III

Exclusion

  • Patients with a history of neuromuscular diseases
  • Patients receiving chronic steroid or immunosuppressive therapy
  • Patients with electrolyte imbalance
  • Patients using medications that affect neuromuscular transmission
  • Patients with severe organ failure in the preoperative period (e.g., liver or renal failure)
  • Patients who refuse to participate in the study
  • Patients requiring emergency surgery
  • Patients using muscle relaxants in the preoperative period

Key Trial Info

Start Date :

June 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 20 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07003061

Start Date

June 1 2025

End Date

September 20 2025

Last Update

June 29 2025

Active Locations (1)

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Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea

Ankara, Yenimahalle, Turkey (Türkiye), 06200