Status:

ACTIVE_NOT_RECRUITING

Metformin Hydrochloride and Empagliflozin Tablets in the Treatment of Type 2 Diabetes

Lead Sponsor:

Sun Yat-sen University

Collaborating Sponsors:

First Affiliated Hospital, Sun Yat-Sen University

Liaoning Health Industry Group Fushun Mining General Hospital

Conditions:

Type 2 Diabetes

Eligibility:

All Genders

18+ years

Brief Summary

The main objective of this study is to evaluate the efficacy and safety of Metformin Hydrochloride and Empagliflozin Tablets in the treatment of type 2 diabetes in real-world clinical settings. A tota...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years, gender unrestricted;
  • Clinically diagnosed with type 2 diabetes;
  • First-time treatment with metformin and empagliflozin tablets;
  • HbA1c test results within 2 weeks prior to enrollment (rapid fingertip test results are acceptable);
  • Voluntary participation in the study and signing of informed consent form.

Exclusion

  • Moderate to severe renal impairment (eGFR \< 45 mL/min/1.73 m²), end-stage renal disease, or dialysis;
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis;
  • A history of severe allergy to empagliflozin, metformin, or any excipient in this product;
  • Currently or within the past month, participation in any other clinical trials;
  • Judged by the investigator to be unsuitable for participation in this study.

Key Trial Info

Start Date :

August 2 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

2600 Patients enrolled

Trial Details

Trial ID

NCT07003191

Start Date

August 2 2023

End Date

December 31 2025

Last Update

June 4 2025

Active Locations (1)

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Endocrinology Department, The First Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, China