Status:
COMPLETED
Long-Term Efficacy and Safety of Once-Weekly Levothyroxine Regimen in Hypothyroid Patients
Lead Sponsor:
Sohag University
Conditions:
Hypothyroidism
Eligibility:
All Genders
30+ years
Brief Summary
Hypothyroidism is a prevalent endocrine disorder characterized by insufficient production of thyroid hormones. Traditional treatment involves daily administration of levothyroxine (L-T4), which can be...
Detailed Description
Hypothyroidism is a prevalent endocrine disorder characterized by insufficient production of thyroid hormones. Traditional treatment involves daily administration of levothyroxine (L-T4), which can be...
Eligibility Criteria
Inclusion
- All included hypothyrodism patients will be euthyroid, and stable on the same L-T4 dose before the start of study.
Exclusion
- 1- patients with thyroid cancer patients requiring suppressive therapy 2-patients with central hypothyroidism 3- pregnancy, coronary heart disease, arrythmia, chronic heart failure 4-patients with liver cirrhosis, renal failure, acute medical, or surgical illness at the time of evaluation to avoid acute and chronic non-thyroidal illness syndromes.
- 4- Patients taking any medications known to interfere with levothyroxine absorption or metabolism (calcium and iron supplements, antiepileptic agents, antacids, proton pump inhibitors, and H2blockers)
Key Trial Info
Start Date :
March 23 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2024
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT07133295
Start Date
March 23 2021
End Date
August 1 2024
Last Update
August 21 2025
Active Locations (1)
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1
sohag faculty of medicine, Sohag
Sohag, Egypt