Status:

NOT_YET_RECRUITING

BeSpoke Decision Support for Patients With Newly Diagnosed Localised Prostate Cancer

Lead Sponsor:

University College, London

Conditions:

Localised Prostate Cancer

Eligibility:

All Genders

Phase:

NA

Brief Summary

The goal of this randomised clinical trial is to assess whether personalised treatment counselling can improve the decision-making experience in patients with a new diagnosis of localised prostate can...

Detailed Description

Recruited patient participants will be randomised into two arms: * Standard of Care (SOC) arm: SOC counselling * Intervention arm: SOC counselling plus access to BeSpoke Decision Support The standar...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Patient-Participants:
  • Newly diagnosed localised prostate cancer
  • Clinically suitable for at least two of the following treatment options:
  • active surveillance
  • focal therapy
  • radical prostatectomy
  • external beam radiotherapy
  • Willing and able to provide informed consent
  • Exclusion Criteria for Patient Participants:
  • Unsuitable for active treatment due to very low risk prostate cancer or significant health issues.
  • Suspicion of metastatic prostate cancer based on clinical or imaging evidence including:
  • Imaging identified suspicious lesion on bone scan, CT, whole-body MRI or PSMA-PET/CT;
  • PSA ≥50 ng/mL.
  • Not able to provide informed consent.
  • Insufficient English proficiency for adequate use of BeSpoke Decision Support. (Patients with support from a family member, friend or partner, to overcome lack of English proficiency will be included.)
  • Enrolled in other localised prostate cancer studies where treatment is assigned rather than chosen by participants, e.g. PART Trial (Partial prostate Ablation vs Radical prostaTectomy)
  • Inclusion criteria for Health Care Professionals:
  • Have seen BeSpoke Decision Support and spoken to patients in the intervention arm.
  • Willing and able to provide written or electronic informed consent
  • Exclusion criteria for Health Care Professionals
  • 1\. No experience of BeSpoke Decision Support.

Exclusion

    Key Trial Info

    Start Date :

    September 1 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 1 2028

    Estimated Enrollment :

    346 Patients enrolled

    Trial Details

    Trial ID

    NCT07135271

    Start Date

    September 1 2025

    End Date

    June 1 2028

    Last Update

    August 22 2025

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