Status:
COMPLETED
Apitoxin Versus Soft Laser for Management of Aphthous Ulceration.
Lead Sponsor:
Tanta University
Conditions:
Apitoxin
Bee Venom Therapy
Eligibility:
All Genders
15-40 years
Phase:
NA
Brief Summary
The current study evaluated the clinical effect and outcome of locally applied bee venom versus low-level laser therapy (LLLT) for the treatment of recurrent aphthous ulceration.
Detailed Description
Recurrent aphthous stomatitis (RAS) is a Painful, idiopathic, and recurrent inflammatory ulceration of the oral cavity. Despite their widespread use, prolonged or frequent application may result in a...
Eligibility Criteria
Inclusion
- Age from 15 to 40 years old.
- Both sexes.
- No current or history of systemic medical problem.
- Non-smoker.
- Suffering from pain due to recurrent aphthous stomatitis (RAS) ulceration on the oral mucosa with the following characteristics:
- Duration of 2 days or less.
- The diameter ≥ 4mm
- Not been subjected to any treatment modalities for at least four weeks before the beginning of the study.
Exclusion
- Presence of other oral mucosal ulcers other than RAS.
- Systemic disease that predisposed them to RAS (e.g., Behçet disease).
- Systemic medical problems.
- Pregnant, lactating, and postmenopausal patients.
- Smoker patients.
- Systemic or topical treatment for RAS less than four weeks before starting the study.
- Any earlier experiences of laser therapy.
Key Trial Info
Start Date :
April 30 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 2 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07135609
Start Date
April 30 2024
End Date
February 2 2025
Last Update
August 22 2025
Active Locations (1)
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1
Tanta University
Tanta, El-Gharbia, Egypt, 31527