Status:

RECRUITING

Sciatic Nerve Stiffness Using Two-Sequences of Lower Limb Neurodynamic Testing: A Shear Wave Elastography Study

Lead Sponsor:

Cairo University

Conditions:

Sciatic Nerve

Eligibility:

All Genders

25-40 years

Brief Summary

The purposes of the study are: 1. To measure differences in Sciatic nerve (SN) stiffness using shear-wave elastography (SWE) during two movement sequences of the lower limb neurodynamic test (LLNT) i...

Detailed Description

As peripheral nerves can exhibit regional variations in their anatomy and mechanical properties, investigating the response of different nerve segments to different loading patterns based on the order...

Eligibility Criteria

Inclusion

  • Thirty participants ranging in age from 25 to 40 years from both genders with a diagnosis of low back pain with radiating leg pain and thirty control group.
  • The main symptoms are low back pain with unilateral leg pain(sciatica) for 3-12 months for group A.
  • Patients with lumbar disc herniation (L4-5) with diagnostic imaging as MRI for group A.
  • Positive straight leg raising are considered for inclusion in the study for group A.
  • Control group must be free from any symptoms of nerve irritation or compression, with normal neurological examination findings, including reflexes, sensation, negative straight leg raising and motor strength.

Exclusion

  • Diabetes mellitus.
  • Any type of polyneuropathy
  • Trauma of lumbar spine
  • Previous history of back surgery
  • Piriformis syndrome.
  • Participants with conditions that reduce image quality on US imaging (thick gluteal subcutaneous fat tissue.
  • Hip joint prosthesis.
  • Professional athletes (Neto et al., 2024).
  • Skin infection

Key Trial Info

Start Date :

August 15 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 28 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT07136441

Start Date

August 15 2025

End Date

February 28 2026

Last Update

September 11 2025

Active Locations (1)

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1

Cairo University

Giza, Egypt