Status:

COMPLETED

Metagenomic Analysis of the Oral Microbiome in Patients With Oral Lichen Planus: A Pilot Study in the Turkish Population

Lead Sponsor:

Kahramanmaras Sutcu Imam University

Conditions:

Oral Lichen Planus

Eligibility:

All Genders

18-80 years

Brief Summary

Lichen planus is a common chronic mucocutaneous inflammatory disease that affects the skin, nails, eyes, urogenital system, and oral mucosa. Oral lichen planus (OLP) specifically occurs in the oral ca...

Detailed Description

Lichen planus is a chronic dermatological disease. It is characterized by papules that are localized in areas exposed to mechanical irritation, mostly in areas of friction from clothing, on the inner ...

Eligibility Criteria

Inclusion

  • • Individuals who agree to participate in the study,
  • Aged between 18 and 75,
  • Individuals with OLP that has clinical and histopathological characteristics according to the World Health Organization FOR HEALTHY INDIVIDUALS; CRITERIA FOR PARTICIPATION IN THE STUDY
  • Individuals who agree to participate in the study,
  • Aged between 18 and 75,
  • Healthy individuals with no systemic disorders

Exclusion

  • • Individuals with oral mucosal diseases other than OLP,
  • Individuals with systemic disorders (autoimmune diseases, hematological diseases, diabetes mellitus, hypertension, infectious diseases, allergic conditions),
  • Use of systemic or topical medication for OLP within the last six months, FOR HEALTHY INDIVIDUALS;
  • CRITERIA FOR EXCLUSION FROM THE STUDY
  • • Individuals with OLP and other autoimmune-related oral mucosal diseases,

Key Trial Info

Start Date :

December 15 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 15 2024

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT07137156

Start Date

December 15 2023

End Date

June 15 2024

Last Update

August 22 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Ayşe Gül Öner Talmaç

Kahramanmaraş, Kahramanmaraş, Turkey (Türkiye), 46000