Status:

RECRUITING

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

Lead Sponsor:

Mayo Clinic

Conditions:

LDL Hyper-responsiveness

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes...

Eligibility Criteria

Inclusion

  • 18 years of age or older
  • LDL-C \>170 mg/dL in response to starting a ketogenic diet

Exclusion

  • Patients who do not consent to blood draw for genetic testing
  • Those with LDL-C \<170 mg/dL on a ketogenic diet

Key Trial Info

Start Date :

September 11 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07137286

Start Date

September 11 2025

End Date

August 1 2027

Last Update

November 20 2025

Active Locations (1)

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Mayo Clinic

Rochester, Minnesota, United States, 55905

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet | DecenTrialz