Status:

NOT_YET_RECRUITING

Quantitative Refractive Crosslinking in Presbyopia Aged Patients

Lead Sponsor:

TECLens, Inc.

Collaborating Sponsors:

Renato Ambrósio, MD - Rio Vision; Tijuca Rio de Janeiro, Brazil

Juan Batlle, Jr. MD - Laser Center; Santo Domingo, Dominican Rep.

Conditions:

Presbyopia

Eligibility:

All Genders

40-65 years

Phase:

NA

Brief Summary

An 'on-eye' UV delivery system for corneal crosslinking can be used safely and effectively to help free presbyopic patients from the need for reading glasses.

Detailed Description

The clinical trial is evaluating the TECLens CXLens Crosslinking System, an investigational treatment using ultraviolet (UV) light (375 nm) with riboflavin (vitamin B2) to strengthen and reshape the c...

Eligibility Criteria

Inclusion

  • Adults aged 40-65 years
  • Healthy cornea
  • Refractive error between +4.0 D and -5.0 D
  • Phakic or monofocal pseudophakic (≥6 months post IOL placement)
  • Visual acuity correctable by ±0.25 D

Exclusion

  • Corneal dystrophy, scarring, or prior corneal crosslinking
  • Astigmatism \>1.0 D
  • Active ocular infection, inflammation, or uncontrolled dry eye
  • Advanced glaucoma or diabetic retinopathy
  • History of delayed corneal healing
  • Pregnancy, breastfeeding, or planning pregnancy during study period
  • Certain medications (e.g., isotretinoin)
  • Recent participation in other investigational drug/device studies (within 30 days)
  • Patients with uncontrolled dry eye or surface disease

Key Trial Info

Start Date :

August 31 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2026

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT07137767

Start Date

August 31 2025

End Date

August 1 2026

Last Update

August 29 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Rio Vision Hospital Oftalmológico

Rio de Janeiro, Brazil

2

Laser Center

Santo Domingo, Dominican Republic