Status:

RECRUITING

Integrating AI in Stroke Neurorehabilitation

Lead Sponsor:

Eodyne Systems SL

Collaborating Sponsors:

Universidad Miguel Hernandez de Elche

Conditions:

Stroke

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The AISN multicenter randomized controlled trial will assess the effectiveness of a novel artificial intelligence (AI)-based clinical decision-support system integrated into the Rehabilitation Gaming ...

Detailed Description

The AISN study addresses the gap in long-term, personalized stroke rehabilitation after hospital discharge by evaluating an enhanced digital therapy platform that combines the clinically validated Reh...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • ≥ 6 months post-stroke
  • Patients presenting a first-ever ischemic or intracerebral hemorrhagic stroke
  • Mild to Moderate unilateral upper limb motor impairment: Medical Research Council proximal and distal upper limb MRC ≥2; Action Research Arm Test: ARAT score \< 50 (0 = no function, 57 = no functional limitation).
  • Age \> 18 years old
  • Able to sit on a chair or a wheelchair and interact with RGS during an entire session
  • Minimal experience with smartphone technology based on the clinician's opinion
  • Willing to participate in the RGS therapy
  • Sign the Informed Consent Form
  • Exclusion Criteria
  • Diagnosis with Epilepsy
  • Severe cognitive capabilities preventing the execution of the experiment or according to clinicians' criteria.
  • Severe associated impairment such as proximal but not distal spasticity, communication disabilities (sensory, Wernicke aphasia or apraxia), major pain (VAS \> 75-100 mm), orthopedic devices that would interfere with the correct execution of the experiment (Modified Ashworth Scale \> 3)
  • Unable to use the RGS app independently according to the clinician's observations and lacking support from a caregiver to use the RGS app
  • No experience with smartphone technology or based on the clinician's opinion.
  • Refusal to sign the Informed Consent
  • Participating or planning to participate in another trial while being part of the present study.

Exclusion

    Key Trial Info

    Start Date :

    October 15 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 30 2026

    Estimated Enrollment :

    192 Patients enrolled

    Trial Details

    Trial ID

    NCT07138495

    Start Date

    October 15 2025

    End Date

    December 30 2026

    Last Update

    December 22 2025

    Active Locations (4)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 1 (4 locations)

    1

    CHU de Limoges

    Limoges, France

    2

    San Camillo Hospital, IRCCS

    Venice, Veneto, Italy, 30126

    3

    UMF

    Cluj-Napoca, Romania

    4

    Parc Sanitari Sant Joan de Deu (SJDD)

    Barcelona, Spain