Status:
RECRUITING
Dexamethasone Versus Magnesium Sulphate as an Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Elective Caesarean Section Under Spinal Anesthesia
Lead Sponsor:
Cairo University
Conditions:
Dexamethasone
Magnesium Sulphate
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
This study aims to compare the efficacy of adding dexamethasone and magnesium sulfate as an adjuvant to bupivacaine in bilateral erector spinae block in postoperative pain control in patients undergoi...
Detailed Description
Caesarean section (CS) is the most common abdominal surgery among women worldwide. Inadequately treated postoperative pain can contribute significantly to morbidity of surgical patients, resulting in ...
Eligibility Criteria
Inclusion
- Age from 18 to 35 years.
- Full-term, singleton, pregnant women.
- American Society of Anesthesiologists (ASA) physical status II.
- Scheduled for elective cesarean delivery under spinal anesthesia.
Exclusion
- Refusal of the patient.
- Emergency caesarean sections.
- Patients having chronic diseases as asthma, cardiovascular disorders (Significant arrhythmias, Severe Valvular diseases, congenital heart diseases, ischemic heart disease, cardiomyopathy, deep venous thrombosis ,and pulmonary embolism)
- Renal impairment (Creatinine level ≥ 2mg/dl, urea ≥ 25mg/dL), liver impairment \[Alanine aminotransferase (ALT) \< 45 U/L, Aspartate aminotransferase (AST) \< 45 U/L\].
- Allergy to the drug enrolled in the study.
- Body mass index (BMI) ≥ 35 kg/m2.
- Hypertensive disorders of pregnancy.
- Contraindication to spinal anesthesia, such as coagulopathy \[platelet count \<150.000, international normalized ratio (INR) \> 1.2\], or local infection.
- Requirement for conversion to general anesthesia after spinal anesthesia will also be excluded.
Key Trial Info
Start Date :
December 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07139522
Start Date
December 1 2023
End Date
December 1 2025
Last Update
August 24 2025
Active Locations (1)
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1
Cairo University
Cairo, Egypt, 12613