Status:

NOT_YET_RECRUITING

Home-Based Photo-Biomodulation for Management of Lymphoedema and Radiation Fibrosis in Patients After Head and Neck Cancer: A Single-Arm Feasibility Trial

Lead Sponsor:

Peter MacCallum Cancer Centre, Australia

Conditions:

Head and Neck Cancer

Eligibility:

All Genders

Phase:

NA

Brief Summary

This feasibility trial will test the use of photo-biomodulation (PBM) therapy, predominantly self-delivered in the patient's home for 12-weeks, following completion of radiotherapy treatment for head ...

Eligibility Criteria

Inclusion

  • Patient has provided written informed consent using the HOME-PBM patient information and consent form
  • Patient is referred to the Lymphoedema Clinic for the management of head and neck lymphoedema and/or radiation fibrosis
  • Previously received curative-intent treatment (surgery and/or \[chemo\]radiotherapy) for mucosal head and neck cancer
  • Patient is able to attend appointments in person
  • Adults aged 18 years or older at Screening
  • Patient able to speak and read English

Exclusion

  • Patient has cognitive impairment that in the opinion of the Investigator would interfere with their ability to participate in the trial (e.g., complete outcome measures, perform the intervention)
  • Residual or recurrent disease within the head and neck
  • Has a diagnosis of photosensitive disorder (cutaneous porphyria, xeroderma pigmentosum, etc.)
  • Patient has tuberculosis or another form of virulent bacteria
  • Patient has a contraindication to receiving PBM treatment
  • Patient has no internet enabled device for telehealth video follow-up appointment

Key Trial Info

Start Date :

September 4 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 31 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT07139782

Start Date

September 4 2025

End Date

October 31 2026

Last Update

August 24 2025

Active Locations (1)

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1

Peter MacCallum Cancer Centre

Melbourne, Victoria, Australia, 3000

Home-Based Photo-Biomodulation for Management of Lymphoedema and Radiation Fibrosis in Patients After Head and Neck Cancer: A Single-Arm Feasibility Trial | DecenTrialz