Status:
NOT_YET_RECRUITING
Renal Oximetry-Guided Anesthesia With Near-Infrared Spectroscopy for Improved Postoperative Outcomes
Lead Sponsor:
Chinese PLA General Hospital
Collaborating Sponsors:
Beijing Tsinghua Changgeng Hospital
Conditions:
Acute Kidney Injury
Eligibility:
All Genders
45+ years
Phase:
PHASE1
Brief Summary
The trial is a prospective, randomized, single-blind, pilot study investigating whether near-infrared spectroscopy (NIRS)-guided optimization of intraoperative renal oxygen saturation (SrtO₂) reduces ...
Eligibility Criteria
Inclusion
- Age ≥ 45 years
- Scheduled for elective hepatectomy
- Planned for general anesthesia with endotracheal intubation
- BMI \< 30 kg/m2
- Preoperative ultrasound shows renal cortical to skin distance ≤ 4 cm
- ASA classification I-III
- Consenting to participate and signing informed consent
Exclusion
- Liver transplantation surgery
- Preoperative renal dysfunction or requirement for dialysis treatment;
- Contraindications to vasoactive drugs such as norepinephrine or dopamine as determined by the clinician;
- Severe cardiopulmonary insufficiency (severe arrhythmia, heart failure, respiratory failure, chronic obstructive pulmonary disease), or a serious cardiovascular or cerebrovascular event within the last six months before randomization (such as acute heart failure, acute myocardial infarction, stroke, etc.);
- Patient refusal to participate or current participation in another experimental study;
- Other factors deemed unsuitable for inclusion by the researcher.
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 30 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT07141693
Start Date
September 1 2025
End Date
May 30 2026
Last Update
August 26 2025
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