Status:

RECRUITING

Fertility Preservation in Children With Solid Tumors: Detection of Residual Disease by a Sensitive Method

Lead Sponsor:

University Hospital, Clermont-Ferrand

Collaborating Sponsors:

University Hospital, Rouen

Conditions:

Neuroblastoma

Ewing Sarcoma

Eligibility:

All Genders

2-45 years

Brief Summary

In prepubertal patients, cryopreservation of ovarian or testicular tissue is currently the only available method for fertility preservation prior to gonadotoxic cancer treatments. However, this approa...

Detailed Description

Ovarian and testicular cryopreservation is the only option to preserve the fertility of children diagnosed with cancer. Cancer treatments such as chemotherapy and radiotherapy can lead to gonadal toxi...

Eligibility Criteria

Inclusion

  • Women of any age diagnosed with a benign cyst requiring laparoscopy may be included.
  • Men of any age diagnosed with a non-obstructive azoospermia may be included.
  • Prepubertal girls and boys diagnosed with neuroblastoma or Ewing sarcoma during infancy may be included.
  • Capable of providing written informed consent to participate in the research study
  • Affiliated with a social welfare service.
  • For prepubertal patients, written informed consent to participate in the research study must be provided by their parents or legal guardians.

Exclusion

  • None

Key Trial Info

Start Date :

February 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

89 Patients enrolled

Trial Details

Trial ID

NCT07141862

Start Date

February 1 2025

End Date

December 31 2027

Last Update

September 3 2025

Active Locations (1)

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1

University hospital

Clermont-Ferrand, Auvergne, France, 63000