Status:
NOT_YET_RECRUITING
Life Expectancy-informed Colorectal Cancer Screening
Lead Sponsor:
Kathryn Martinez
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Colorectal Cancer Control and Prevention
Eligibility:
All Genders
76+ years
Phase:
NA
Brief Summary
The purpose of this study is to improve life-expectancy concordant colorectal cancer screening for adults over 75 years through design and testing of a life expectancy notification to clinicians deliv...
Detailed Description
The purpose of this study is to improve life-expectancy concordant colorectal cancer screening for adults over 75 years through design and testing of a life expectancy notification to clinicians deliv...
Eligibility Criteria
Inclusion
- Aim 1a: Patients must meet all the inclusion criteria listed below to be included:
- \> 75 years of age
- Resident of Ohio
- Had at least one Internal Medicine or Family Medicine visit at Cleveland Clinic Health System between January 1, 2007, and September 1, 2022.
- Aim 1b: Clinicians must meet all the inclusion criteria listed below to be included:
- Internal Medicine or Family Medicine clinician (MD, DO, or APP) practicing at Cleveland Clinic Health System in Northeast Ohio
- Saw ≥10 study-eligible patients, defined as patients aged \>75 years who were due or overdue for colorectal cancer screening, between 2024-2025
- With a colonoscopy ordering rate for patients \>75 years in either the top quarter of the distribution of all eligible clinicians or bottom quarter of all eligible clinicians
- Aim 2: Clinics must meet all the inclusion criteria listed below to be included:
- • Internal Medicine or Family Medicine clinical site included in the Cleveland Clinic Health System in Northeast Ohio or Florida
- Clinicians must meet all the inclusion criteria listed below to be included:
- Currently practicing in Internal or Family Medicine as an attending clinician
- Saw ≥10 study-eligible patients, defined as patients aged \>75 years who were due or overdue for colorectal cancer screening, between 2024-2025
- Patients must meet all the inclusion criteria listed below to be included:
- \>75 years of age
- Have not received a colonoscopy in the prior 10 years
- Have not received a FOBT/FIT in prior year
- Had a visit in Internal Medicine or Family Medicine between January 1, 2026 and January 1, 2028
Exclusion
- All candidates meeting any of the exclusion criteria at baseline will be excluded from study participation.
- Aim 1a:
- Patients aged ≤75 years
- Patients who did not have at least one subsequent Internal or Family Medicine visit in Ohio within two years from the date of their baseline visit
- Patients being actively treated for non-skin cancer
- Aim 1b:
- Clinicians who are not in the top or bottom quarter of the distribution of colonoscopy orderers for patients aged \>75 years
- Trainees/residents
- Saw \<10 study-eligible patients between 2024-2025
- Aim 2:
- Patients aged \<75 years
- Patients up to date with colorectal cancer screening (colonoscopy within 10 years or FOBT/FIT/Cologuard within the past year)
Key Trial Info
Start Date :
August 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2029
Estimated Enrollment :
15000 Patients enrolled
Trial Details
Trial ID
NCT07141901
Start Date
August 1 2026
End Date
March 1 2029
Last Update
September 24 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cleveland Clinic
Cleveland, Ohio, United States, 44195