Status:

RECRUITING

The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal

Lead Sponsor:

The Cooper Health System

Collaborating Sponsors:

University of California, Davis

Washington University School of Medicine

Conditions:

Surgical Wound Infection

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The goal of this clinical trial is to learn if reducing bacterial load on the skin and nostrils with topical antibacterial soap and ointment, respectively, reduces rate of infection in surgical sites ...

Detailed Description

The goal of this clinical trial is to learn if reducing bacterial load on the skin and nostrils with topical antibacterial soap and ointment, respectively, reduces rate of infection in surgical sites ...

Eligibility Criteria

Inclusion

  • Age at least 18 years old
  • Scheduled to undergo surgical treatment for skin cancer on the lower extremities and have no other surgeries scheduled in the coming weeks after the procedure
  • Will have a surgical wound that will be left open to heal by secondary intention

Exclusion

  • Age under 18 years old
  • Have a known allergy to chlorhexidine or mupirocin
  • Have a history of Staphylococcus aureus infection
  • Have a history of heart valve or joint replacement surgery requiring pre-operative antibiotics

Key Trial Info

Start Date :

March 13 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2030

Estimated Enrollment :

848 Patients enrolled

Trial Details

Trial ID

NCT07142408

Start Date

March 13 2023

End Date

December 1 2030

Last Update

August 26 2025

Active Locations (1)

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1

The Center for Dermatologic Surgery at Cooper University Health Care

Marlton, New Jersey, United States, 08053