Status:
NOT_YET_RECRUITING
Exercise and/or HMB in Older Diabetes With Low Muscle Mass
Lead Sponsor:
Wu Shangling
Conditions:
Diabetes
Low Muscle Mass
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
The investigators aimed to examine if β-hydroxy-β-methylbutyrate (HMB) supplementation enhances the effects of exercise on muscle mass, physical performance and insulin resistance and observe potentia...
Detailed Description
The interaction between exercise and nutritional supplementation is unclear among older diabetes at risk of sarcopenia. The investigators aimed to examine if β-hydroxy-β-methylbutyrate (HMB) supplemen...
Eligibility Criteria
Inclusion
- Aged 60-80 ;
- Diagnosis of T2DM
- Low muscle mass: met a reference value for low muscle mass defined by the Asian Working Group for Sarcopenia (AWGS) criteria with skeletal muscle index \<5.7 kg/m2 for women and \<7.0 kg/m2 for men
Exclusion
- Individuals who had an organic disease of the nervous system;
- Who were restricted from engaging in exercise by a medical doctor;
- Who was unconscious and unable to complete the questionnaire;
- Who used other supplementations for muscle mass gain;
- Who had impaired cardiac, kidney, or liver function.
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT07142941
Start Date
September 1 2025
End Date
December 31 2027
Last Update
August 27 2025
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