Status:

NOT_YET_RECRUITING

Safety and Effectiveness of PreserFlo and XEN Stents With or Without Amniotic Membrane in Glaucoma Surgery

Lead Sponsor:

Nova Scotia Health Authority

Conditions:

Glaucoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Glaucoma is one of the leading causes of permanent blindness in the world. It happens when the optic nerve-the connection between the eye and the brain-is damaged. As this damage gets worse, vision is...

Detailed Description

Glaucoma is the leading cause of permanent blindness worldwide. Glaucoma is damage to the optic nerve, which sends information from the eye to the brain. This damage causes vision to weaken. Treatment...

Eligibility Criteria

Inclusion

  • Age 18 years and older
  • Patients selected for PreserFlo microshunt surgery and XEN stent alone or in combination with cataract surgery.
  • Ability to comprehend the study procedures

Exclusion

  • Unwilling or unable to give consent
  • Unable to come for scheduled post-operative visits
  • Pregnant or nursing women
  • Previous cyclodestructive procedures, scleral buckling procedures, or presence of silicone oil
  • Conjunctival scarring precluding a glaucoma surgery superiorly
  • Active iris neovascularization or active proliferative retinopathy
  • Vitreous in the anterior chamber for which a vitrectomy is anticipated.
  • Previous trabeculectomy, tube-shunt implantation, or surgeries that shunt aqueous outflow into the subconjunctival space

Key Trial Info

Start Date :

December 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

156 Patients enrolled

Trial Details

Trial ID

NCT07143708

Start Date

December 1 2025

End Date

December 31 2027

Last Update

August 27 2025

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