Status:
RECRUITING
Iron Absorption From Plant Heme Iron
Lead Sponsor:
ETH Zurich
Conditions:
Iron Deficiency (ID)
Iron Absorption
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
Heme, an iron protoporphyin IX complex, consists of a ferrous ion captured in a porphyrin ring acting as a tetradentate ligand. The unique features of heme iron -its unusually high absorption in foods...
Eligibility Criteria
Inclusion
- Serum ferritin \< 45 µg/L (iron depleted)
- Body weight \< 70 kg
- Body mass index 18,5 - 24,9 kg/m2 (normal weight)
Exclusion
- Hb \< 120 g/L (anemia)
- CRP \> 5 µg/L (inflammation)
- Strict vegan and vegetarians
- Any metabolic, gastrointestinal kidney or chronic disease
- Consumption of mineral and vitamin supplements since screening and over the study period until last blood sample collection
- Blood transfusion over the past 6 months
- blood donation over the past 6 months
- Significant blood loss (accident, surgery) over the past 6 months
- Women who are pregnant or breast feeding
- Smoker (\> 1 cigarette per week)
- Continuous/long-term use of medication (except for contraceptives)
- Therapeutic iron infusion over the past 6 months,
- Known hypersensitivity or allergy to iron supplements,
- Intention to become pregnant during the course of the studies,
- Known or suspected non-compliance, drug or alcohol abuse,
- Inability to follow the procedures of the studies, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
- Participation in another study with investigational drug within the 30 days preceding and during the present studies,
- Enrolment of the investigator, his/her family members, employees and other dependent persons
Key Trial Info
Start Date :
September 22 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 18 2025
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT07143890
Start Date
September 22 2025
End Date
December 18 2025
Last Update
December 24 2025
Active Locations (1)
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1
ETH Zurich, Laboratoy of Clinical Biopharmacy
Zurich, Switzerland, 8092