Status:

RECRUITING

AI Assessment of Low-Gradient Aortic Stenosis Severity Based on Echocardiography

Lead Sponsor:

National Institute of Cardiology, Warsaw, Poland

Collaborating Sponsors:

The Institute of Bioorganic Chemistry, Polish Academy of Sciences

Conditions:

Low-gradient Aortic Stenosis

Aortic Stenosis

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to evaluate the effectiveness of an artificial intelligence (AI) model developed by the investigators for identifying severe low-gradient aortic valve stenosis. Accurate a...

Detailed Description

This study is a prospective multicenter observational validation of an artificial intelligence (AI) model for differentiating severe low-gradient from moderate aortic stenosis using transthoracic echo...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years
  • Clinical suspicion of significant low-gradient aortic stenosis
  • Echocardiographic examination performed for clinical indications
  • Ability to provide informed consent

Exclusion

  • Previous aortic valve intervention (surgical or transcatheter)
  • Inadequate image quality precluding echocardiographic analysis
  • Concomitant severe valvular disease (severe mitral stenosis or mitral/aortic regurgitation) that could confound assessment
  • Patients unwilling or unable to provide informed consent

Key Trial Info

Start Date :

August 20 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 20 2026

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT07144189

Start Date

August 20 2025

End Date

August 20 2026

Last Update

December 2 2025

Active Locations (1)

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Department of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland

Warsaw, Masovian Voivodeship, Poland