Status:

NOT_YET_RECRUITING

Low Powered Colorectal Anastomosis After Rectal Excision (OASIS)

Lead Sponsor:

Bordeaux Colorectal Institute

Conditions:

Rectal Cancer

Surgery Indication

Eligibility:

All Genders

18+ years

Brief Summary

The objectiive of this prospective, international cohort is to compare two anastomotic techniques (DS vs TTSS) by collecting data during the surgery, and postoperatively (morbidity and functional outc...

Detailed Description

There are a variety of available anastomotic techniques to facilitate restorative surgery following total mesorectal excision (TME) for rectal cancer. However, there is no good quality evidence demons...

Eligibility Criteria

Inclusion

  • Age ≥ 18
  • Patients with rectal cancer lower than 12 cm from the anal verge requiring either a stapling anastomosis below 7 cm from the anal verge,
  • Patients with powered mechanical anastomosis (INTOCARE devices)
  • Patients with no metastasis
  • Patients operated on by mini-invasive rectal excision (laparoscopic, robotic or TaTME);
  • Patients with or without defunctioning ileostomy;
  • Patients with or without neoadjuvant treatment;
  • Patient who benefits by medicare system;
  • Signed and dated informed consent

Exclusion

  • Patients with handsewn anastomosis
  • Patients with perforated rectal cancer or preoperative pelvic sepsis ;
  • Patients with inflammatory bowel disease;
  • Patients operated on in emergency ;
  • Patients with extended-TME or pelvic exenteration;
  • Pregnancy or breast feeding period
  • Legal incapacity or physical, psychological social or geographical status interfering with the patient's ability to agree to participate in the study
  • Persons deprived of liberty or under guardianship

Key Trial Info

Start Date :

September 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2029

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT07146334

Start Date

September 1 2025

End Date

September 1 2029

Last Update

August 28 2025

Active Locations (15)

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Page 1 of 4 (15 locations)

1

Hôpital Universitaire de Belgique

Leuven, Belgium

2

Hôpital Universitaire McGill

Montreal, Canada

3

CHU de Quebec

Québec, Canada

4

Hôpital Universitaire de Shanghai

Shanghai, China