Status:
COMPLETED
Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness
Lead Sponsor:
Zahoor khan
Collaborating Sponsors:
HITEC-Institute of Medical Sciences
Conditions:
Symptomatic Irreversible Pulpitis
Eligibility:
All Genders
18-45 years
Phase:
PHASE3
Brief Summary
This clinical study investigates whether the combination of ibuprofen and serratiopeptidase as oral premedication can enhance the effectiveness of the inferior alveolar nerve block (IANB) in patients ...
Detailed Description
Detailed Description of the Study Title Evaluation of Combined Effect of Oral Premedication on Enhancing the Effectiveness of Inferior Alveolar Nerve Block in Mandibular Teeth with Symptomatic Irrever...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Age group of subjects between 18-45 years
- Normal PDL appearance on IOPA
- No analgesics taken 12 hours prior to study
- Mandibular molars and premolars with deep carious lesion having sign and symptom of symptomatic irreversible pulpitis
- Exclusion criteria:
- Presence of periapical radiolucency on IOPA
- Teeth tender to percussion /traumatic teeth
- Allergy to medications/anesthetic solution
- Pregnant patient \& systemic illness
- Patient in which local anesthesia is not effective in first attempt
- Patient not giving consent
Exclusion
Key Trial Info
Start Date :
November 23 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 23 2024
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT07146997
Start Date
November 23 2023
End Date
November 23 2024
Last Update
September 9 2025
Active Locations (1)
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1
HITEC-IMS Taxila
Rawalpindi, Punjab Province, Pakistan, 47080