Status:
RECRUITING
Functional Capacity, Sleep Quality, and Cognitive Function in Obesity Hypoventilation Syndrome
Lead Sponsor:
Bezmialem Vakif University
Collaborating Sponsors:
Istanbul University
Conditions:
Obesity Hypoventilation Syndrome (OHS)
Eligibility:
All Genders
18-65 years
Brief Summary
Introduction: Obesity Hypoventilation Syndrome (OHS) is defined as the coexistence of obesity (BMI ≥ 30 kg/m²), daytime hypercapnia (PaCO₂ \> 45 mmHg) in the absence of other causes of hypoventilatio...
Detailed Description
Obesity Hypoventilation Syndrome (OHS) is defined as the combination of obesity (BMI ≥ 30 kg/m²), daytime hypercapnia (PaCO₂ \> 45 mmHg) in the absence of other pathologies causing hypoventilation, an...
Eligibility Criteria
Inclusion
- Age between 18 and 65 years
- Diagnosed with OHS by a pulmonologist
- For individuals with simple obesity: BMI between 30 and 40 kg/m², Apnea-Hypopnea Index (AHI) \< 5 on polysomnography, or STOP-Bang score \< 3
- Ability to communicate in written and spoken Turkish
Exclusion
- Presence of any additional severe respiratory disease
- Presence of orthopedic, neurological, cardiovascular, or respiratory conditions preventing exercise testing
- For individuals with simple obesity: presence of OSAS risk factors such as severe snoring or witnessed apnea
- Presence of any psychological or psychiatric disorder that could affect cognitive functions
Key Trial Info
Start Date :
January 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 15 2025
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT07147153
Start Date
January 1 2025
End Date
October 15 2025
Last Update
August 28 2025
Active Locations (1)
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1
Istanbul University, Istanbul Faculty of Medicine
Istanbul, Turkey (Türkiye)