Status:

RECRUITING

Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy

Lead Sponsor:

University of California, San Francisco

Conditions:

Gender Dysphoria

Mastectomy

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

The goal of this randomized, prospective, interventional clinical trial is to evaluate the use of Brijjit® in reducing the incidence of hypertrophic scarring in individuals undergoing gender-affirming...

Detailed Description

The hypothesis of this study is that the use of Brijjit® Force-Modulating Tissue Bridge devices will reduce the incidence of hypertrophic scarring as measured by objective and subjective factors compa...

Eligibility Criteria

Inclusion

  • Age ≥ 19
  • Undergoing double incision gender affirming mastectomy
  • Ability to adhere to Brijjit therapy after surgery
  • Willing to return for follow-up visits and undergo study evaluations

Exclusion

  • History of keloid formation
  • Radiation therapy history
  • Prior surgeries of the chest or breast
  • History or use following prescription medications: 1) accutane within the past year. 2) chronic systemic steroids
  • Active smoker
  • Disorder known to negatively affect wound healing (autoimmune, connective tissue, uncontrolled diabetes)
  • Any other condition determined by PI to preclude subject from joining study

Key Trial Info

Start Date :

September 20 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2027

Estimated Enrollment :

78 Patients enrolled

Trial Details

Trial ID

NCT07147166

Start Date

September 20 2025

End Date

June 1 2027

Last Update

August 28 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UCSF Department of Plastic & Reconstructive Surgery

San Francisco, California, United States, 94131

Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy | DecenTrialz