Status:
NOT_YET_RECRUITING
Characterization of EVs (Extracellular Vesicles)/miRNAs (microRNAs) From Human Follicular Fluid
Lead Sponsor:
University Hospital, Ghent
Conditions:
Extracellular Vesicles
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
* Background Extracellular vesicles (EVs) are membrane-bound vesicles found in all biological fluids. They contain various regulatory molecules, including microRNAs (miRNAs). It is hypothesized that E...
Eligibility Criteria
Inclusion
- Signed informed consent.
- Oocyte retrieval planned for an coPGT-M ICSI trajectory at Ghent University Hospital.
- BMI 18,5-30 kg/m2.
- Normal karyotype of patient and partner.
- Ovarian stimulation protocol: PPOS (progestin-primed ovarian stimulation) with recombinant gonadotropins and GnRH agonist trigger.
- A minimum of 5 growing follicles during ovarian stimulation.
Exclusion
- Diagnosis of endometriosis
- Diagnosis of PCOS according to Rotterdam criteria
- Poor ovarian responders according to Bologna criteria
- Severe male subfertility: semen concentration \< 5 million/ml or TESE
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT07148284
Start Date
September 1 2025
End Date
December 1 2025
Last Update
August 29 2025
Active Locations (1)
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1
Ghent University Hospital
Ghent, Belgium, 9000