Status:
NOT_YET_RECRUITING
Evaluation of Resveratrol and Its Loaded Nanoparticles on Acanthamoeba
Lead Sponsor:
Assiut University
Conditions:
Corneal Ulcer Caused by Acanthamoeba
Eligibility:
All Genders
Brief Summary
Acanthamoeba is a free-living amoeba responsible for severe human infections. There are at least twenty-two different genotypes of Acanthamoeba (T1-T22). T4 is the most common virulent genotype, mainl...
Detailed Description
: 1-Specimen collection using: A- Corneal swabs. B- Corneal scraping and superficial keratectomy. C- Contact lenses and contact lens solutions. 2-Culture: The collected samples will be cultivated on ...
Eligibility Criteria
Inclusion
- Patients presented with keratitis to the outpatient clinic.
- Patients presented with corneal ulcers to the outpatient clinic.
Exclusion
- Patients presented with corneal ulcers caused by pathogens rather than Acanthamoeba (bacterial, viral or fungal).
- Patients presented with other eye conditions that act as confounding variable as corneal perforation, severe dry eye, glaucoma, scleritis and active uveitis.
- Patients with history of previous ocular surgery or corneal transplant.
Key Trial Info
Start Date :
October 15 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2028
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT07148752
Start Date
October 15 2025
End Date
November 1 2028
Last Update
August 29 2025
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