Status:
NOT_YET_RECRUITING
Association of Serum Interleukin-33 Levels With Clinical Manifestations in Systemic Lupus Erythematosus
Lead Sponsor:
Assiut University
Conditions:
SLE
Eligibility:
All Genders
18+ years
Brief Summary
This is a case-control study investigating serum IL-33 levels and their association with clinical manifestations in systemic lupus erythematosus (SLE). The study compares IL-33 levels in three groups:...
Detailed Description
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with variable clinical presentations, ranging from mild symptoms to life-threatening organ damage. Lupus nephritis, a severe renal ma...
Eligibility Criteria
Inclusion
- Adults aged 18 years and older.
- Diagnosed with systemic lupus erythematosus according to the American College of Rheumatology (ACR) criteria.
- For the lupus nephritis group: confirmed diagnosis of lupus nephritis based on clinical, laboratory, and renal biopsy findings.
- For the control group: healthy individuals matched for age and sex, with no history of autoimmune or renal diseases.
Exclusion
- Patients with other autoimmune diseases. Patients with chronic infections or malignancies. Pregnant or lactating women. Patients with end-stage renal disease (ESRD) or on dialysis. Individuals who refuse to provide informed consent.
Key Trial Info
Start Date :
August 30 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07149402
Start Date
August 30 2026
End Date
December 30 2027
Last Update
September 2 2025
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