Status:

COMPLETED

Efficacy of Levofloxacin Versus Ciprofloxacin in the Treatment of Childhood Typhoid Fever

Lead Sponsor:

Avicenna Medical College Lahore

Conditions:

Typhoid

Fever

Eligibility:

All Genders

1-12 years

Phase:

PHASE2

Brief Summary

Sample size of 360 children with typhoid fever were enrolled and randomly divided in two groups. All the children were enrolled in the trial from Pediatrics emergency. Informed consent was obtained fr...

Eligibility Criteria

Inclusion

  • Children of age 1-12 years
  • Typhoid fever
  • Confirmed on blood culture

Exclusion

  • Recurrent typhoid within 3 months
  • Intestinal perforation
  • Evidence of progressive or complicated disease
  • Inability to swallow oral medication
  • Hypersensitivity to trial drugs
  • Already taken fluoroquinolone, third generation cephalosporin or macrolide in last week

Key Trial Info

Start Date :

February 7 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 7 2025

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT07150065

Start Date

February 7 2025

End Date

August 7 2025

Last Update

September 2 2025

Active Locations (1)

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Avicenna Hospital Lahore

Lahore, Punjab Province, Pakistan, 54000